Just a few days ago we looked at a real guitar that can control Rock Band 3, but now Fender has announced that their Squire Stratocaster for Rock Band 3 will arrive on March 1st 2011 for $280.
Whoa, look at this Rock Band 3 Fender Mustang Pro guitar and keyboard. In the game's new "pro mode," you'll have to press small buttons on the guitar's fretboard where the real notes would be to win the game. Along with that will be a new 25-key MIDI keyboard with similar requirements, both changing the game from matching up colors with on-screen graphics to actually playing a musical instrument.
I got an insider tip from "Sean" that Harmonix is looking for someone with elite keyboard skills. As you can see by scrolling to the bottom of this page, Harmonix is looking to hire someone handy with the organ....