In 1953, at age 27, Henry Molaison underwent a surgical procedure to try to control his seizures. This procedure involved removing a few pieces of his brain, and it worked, in that the seizures became manageable. However, it also messed Henry up in some fairly serious ways, most significantly that he became unable to create any new memories. He also lost the ability to tell when he was hungry, thirsty, or tired. Interestingly, he could still learn new things, he just couldn't remember learning them, which gave the neurologists who worked with Henry some fascinating insights into which pieces of the brain are responsible for doing what.
Henry participated in experiments for decades, at least partially because to him, the experiments were always brand new experiences, and so he never got bored. When he died in 2008, he donated his brain to science. Science then flash-froze his brain and sliced it up into nearly 2,401 sections for further study, a process which you can watch taking place in the video below.
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